KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DENND5B
All Species:
26.67
Human Site:
S101
Identified Species:
83.81
UniProt:
Q6ZUT9
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZUT9
NP_659410.3
1274
145020
S101
N
K
D
P
Q
F
H
S
F
I
I
T
R
E
D
Chimpanzee
Pan troglodytes
XP_001138253
1296
147416
S123
N
K
D
P
Q
F
H
S
F
I
I
T
R
E
D
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534846
1411
160944
S238
N
K
D
P
Q
F
H
S
F
I
I
T
R
E
D
Cat
Felis silvestris
Mouse
Mus musculus
A2RSQ0
1274
144611
S101
N
K
E
P
Q
F
H
S
F
I
I
T
R
E
D
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001235265
1482
166462
S309
N
R
D
P
Q
L
H
S
F
I
I
T
R
E
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6NXD8
1311
147682
S115
S
L
A
P
H
F
H
S
F
L
I
T
R
E
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395592
1282
146285
S98
S
V
E
P
T
F
H
S
F
V
L
T
K
E
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781573
1628
184518
T124
S
P
V
H
Q
C
Y
T
T
K
A
Y
T
L
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.3
N.A.
86.6
N.A.
95.3
N.A.
N.A.
N.A.
79.4
N.A.
73
N.A.
N.A.
45.5
N.A.
35.5
Protein Similarity:
100
98.3
N.A.
88.5
N.A.
97.4
N.A.
N.A.
N.A.
83.1
N.A.
83.4
N.A.
N.A.
64.1
N.A.
49.9
P-Site Identity:
100
100
N.A.
100
N.A.
93.3
N.A.
N.A.
N.A.
86.6
N.A.
66.6
N.A.
N.A.
53.3
N.A.
6.6
P-Site Similarity:
100
100
N.A.
100
N.A.
100
N.A.
N.A.
N.A.
93.3
N.A.
80
N.A.
N.A.
86.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
13
0
0
0
0
0
0
0
13
0
0
0
0
% A
% Cys:
0
0
0
0
0
13
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
50
0
0
0
0
0
0
0
0
0
0
0
88
% D
% Glu:
0
0
25
0
0
0
0
0
0
0
0
0
0
88
0
% E
% Phe:
0
0
0
0
0
75
0
0
88
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
13
13
0
88
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
63
75
0
0
0
0
% I
% Lys:
0
50
0
0
0
0
0
0
0
13
0
0
13
0
0
% K
% Leu:
0
13
0
0
0
13
0
0
0
13
13
0
0
13
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
63
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
13
0
88
0
0
0
0
0
0
0
0
0
0
13
% P
% Gln:
0
0
0
0
75
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
13
0
0
0
0
0
0
0
0
0
0
75
0
0
% R
% Ser:
38
0
0
0
0
0
0
88
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
13
0
0
13
13
0
0
88
13
0
0
% T
% Val:
0
13
13
0
0
0
0
0
0
13
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
13
0
0
0
0
13
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _